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Adipose Tissue and Cancer - download pdf or read online

By Nikki A. Ford, John DiGiovanni, Stephen D. Hursting (auth.), Mikhail G. Kolonin (eds.)

ISBN-10: 1461476593

ISBN-13: 9781461476597

ISBN-10: 1461476607

ISBN-13: 9781461476603

Recent experiences have proven that cells from adipose tissue are able to trafficking to tumors, hence allowing paracrine motion of adipokines from in the tumor microenvironment. elevated tumor vascularization, immune procedure suppression and direct results on malignant telephone survival and proliferation were investigated as mechanisms regulated by means of adipokines. The objective of this ebook is to debate info pointing to the function of adipose tissue in melanoma and to dissect person mechanisms by which adipose tissue extra or limit may perhaps impact melanoma progression.

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Example text

Ann Surg Oncol. 2008;15:1918–22. 34. Doria-Rose VP et al. Body mass index and the risk of death following the diagnosis of colorectal cancer in postmenopausal women (United States). Cancer Causes Control. 2006;17:63–70. 35. Asghari-Jafarabadi M et al. Site-specific evaluation of prognostic factors on survival in Iranian colorectal cancer patients: a competing risks survival analysis. Asian Pac J Cancer Prev. 2009;10:815–21. 36. Shibakita M et al. Body mass index influences long-term outcome in patients with colorectal cancer.

A plethora of reports have demonstrated that MSC secrete proangiogenic factors upon tumor engraftment and serve as vascular progenitor cells in pathological tissues [66]. Importantly, upregulation of stromal cell circulation has been detected in peripheral blood of cancer patients [67]. 22 C. Bellows and H. Tilg While the dependence of tumor growth on bone marrow-derived progenitors is unequivocal [68], it was recently realized that circulating stromal progenitor cells from other organs also contribute to postnatal neovascularization [69].

Offerhaus GJ, De Feyter EP, Cornelisse CJ, et al. The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma. Gastroenterology. 1992;102:1612–9. 46. Bell SM, Scott N, Cross D, et al. Prognostic value of p53 over-expression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology. 1993;104:57–64. 47. Wolin KY, Yan Y, Colditz GA. Physical activity and risk of colon adenoma: a meta-analysis. Br J Cancer. 2011;104:882–5. 48. Wolin KY, Yan Y, Colditz GA, Lee IM.

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Adipose Tissue and Cancer by Nikki A. Ford, John DiGiovanni, Stephen D. Hursting (auth.), Mikhail G. Kolonin (eds.)


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