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Advances in Cancer Research, Vol. 28 - download pdf or read online

By George Klein, Sidney Weinhouse (Eds.)

ISBN-10: 0120066289

ISBN-13: 9780120066285

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VII. The Significance of Fetal and Ectopic Proteins It is accepted dogma that every diploid cell, reproductive or somatic, carries the whole of the genetic information present in the zygote from which it arose. A striking demonstration of the implied potentialities of the dogma is provided by the extensive studies that have been made on fetal or ectopic proteins present in or released from human cancers. For more or less adventitious reasons, most research on fetal proteins has concerned a-fetoprotein from liver tumors (Abelev, 1968) and the so-called carcino-embryonic antigen from colonic carcinoma (Gold and Freedman, 1965).

230,367-377. Nowell, P. C. In “Chromosomes and Cancer” (J. ), pp. 267-285. Wiley, New York. Outzen, H. , Custer, R. , and Prehn, R. T. Ado. E x p . Med. Biol. 64,383-386. Potter, V. R. Proc. Cancer Res. Con$ 8, 9-30. Pratt, R. , and Martin, G. R. Proc. Natl. Acad. Sci. A. 72, 874-877. Robbins, J. , Kraemer, K. , Lutzner, M. , Festoff, B. , and Coon, H. G. (1974). Ann. Intern. Med. 80, 221-248. Roe, F. J. C. Proc. R. SOC. Med. 66,23-26. Sedgwick, S. G. Proc. Natl. Acad. Sci. U S A . 72, 2753-2757.

Therapeutic Manipulations in Organ Transplant Recipients . . . . . . . . I11. Transplanted Neoplasms ............................................... IV. De Nouo Cancers ............... A . Incidence .............. B. Age of Patients .................................................... C . Sex ofpatients ..................................................... D . Time of Appearance of Cancers after Transplantation ................. E . Previous Cancers in the Recipients ..................................

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Advances in Cancer Research, Vol. 28 by George Klein, Sidney Weinhouse (Eds.)


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