By Leslie J. DeGroot (auth.), Barry B. Bercu, Dorothy I. Shulman (eds.)
Perinatal difficulties in thyroid gland body structure are universal yet advanced and current a diagnostic challenge for the first clinician. In December 1990, a global team of simple and medical investigators accrued in Longboat Key, Florida to handle those concerns. The individuals integrated internists, obstetricians, pedia tricians, neurologists, pathologists and uncomplicated scientists in mobile metabolism, endocrine body structure, and molecular biology. The displays contained inside of this e-book collect their most present and very important examine on the topic of the sphere of perinatal thyroidology. This booklet relies at the dynamic and fruitful alternate of the contributors on the symposium. we're indebted to those contributors whose worthwhile insights and efforts are contained inside of this article. Barry B. Bercu Dorothy I. Shulman vii CONTENTS consultation I Mechanism of Thyroid Hormone motion 1 Leslie J. DeGroot Thyroid procedure Ontogeny within the Sheep: A version for Precocial Mammalian Species • . . • • eleven Delbert A. Fisher Pathologic reviews of Fetal Thyroid 27 improvement • • • • • • • Douglas R. Shanklin Thyroid Hormone keep an eye on of mind and Motor improvement: Molecular, Neuroanatomical, forty seven and Behavioral experiences • • • • • • • S. A. Stein, P. M. Adams, D. R. Shanklin, G. A. Mihailoff, and M. B. Palnitkar The Thyroidectomized Pregnant Rat: An Animal version to review Fetal results of Maternal Hypothyroidism 107 Susan P. Porterfield and Chester E.
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GAR 25-28 weeks. Birth weight 640 g, lived 43 days. Twinned with a grade 1 chorioma. Varied follicles with some retained colloid. Lesser survivals in this maturity class often have more colloid, suggesting a depletion or drawing down effect due to the principal intercurrent and ultimately fatal disease. Ventilator lung disease with multiple small and large lung abscesses. Hematoxylin and eosin stain. Original magnification, 100X. impermeability to thyroxIne as limIting factors in placental transport of thyroxine [1964) as well a possible early role for chorionic thyrotropin .
This will be described and discussed below. Figure 1. Thyroid folliculogenesis in the first half of human gestation, a period of organogenesis, relatively slow fetal growth. 0 cm crown-rump length (CRL). , no matrix congealed by formalin (Shanklin, 1964; Morada, 1968)). Loose conconnective tissue; the thyroid lobules are not compact. Gestational age (GA) equivalent to 18 weeks, menstrual age. Hematoxylin and eosin stain. Original magnification, 100X. PATHOLOGIC STUDIES OF FETAL THYROID DEVELOPMENT 29 Figure 2.
Prenatal and early postnatal ontogenesis of the human motor cortex: a golgi study. I. The sequential development of the cortical layers. Brain Res. : Postmortem pulmonary edema; differential susceptibility in newborn and adult rabbits. Pathol. H. Wollman: Fine structure of a fifth type of epithelial cell in the thyroid gland of the C3H mouse. Rec. : The morphogenesis of the follicles in the human thyroid gland. Anat. : The cytophysiology of thyroid cells. Rev. Cytol. P. Bloch: Fetal blood sampling in the management of intrauterine thyrotoxicosis.
Advances in Perinatal Thyroidology by Leslie J. DeGroot (auth.), Barry B. Bercu, Dorothy I. Shulman (eds.)