By Charles J. Vecht MD, PhD (auth.), David Schiff MD, Patrick Y. Wen MD (eds.)
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Extra info for Cancer Neurology in Clinical Practice
Since headache is a very common symptom in otherwise healthy people, the physician's role is to identify those few patients in whom the headache is caused by a brain tumor and to reassure the rest. The purpose of this chapter is to elucidate the cause of headache in brain tumors, to describe the characteristics of headaches in patients with brain tumors (primary or metastatic), to identify the factors that cause these headaches and to provide a diagnostic and management approach. gical and clinical features of headaches in patients WIth bram tumors will be presented to aid the clinician in differentiating benign headaches from those requiring further investigation.
This correlates quite well with what is seen clinically as revealed by contrast enhanced computed tomography (CT) and magnetic resonance imaging (MRI): generally, it is tumors involving white matter that have consequential mass effect due to edema. Such instances provide as good an example of the clinical reality of vasogenic edema as one can see. " Cytotoxic edema, on the other hand, is the type "in which a noxious factor directly effects the structural elements ofthe parenchyma producing intracellular swelling, vascular permeability remaining relatively undisturbed.
Microvascular abnormalities in virally induced canine brain tumors: structural bases for altered blood-brain barrier function. J Neurol Sci 1972;17:29-39. 26. VickNA. Brain tumor microvasculature. In: Brain Metastasis. Weiss L, Gilbert HA, Posner JG, eds. K. Hall & Company, Boston, 1980, pp. 115-133. 27. Nakagaw~ H, Groothuis DR, Owens ES, Fenstermacher JD, Patlak CS, Blasberg RG. Dexamethasone effects on  Albumen distribution in experimental RG-2 gliomas and adjacent brain. J Cereb Blood Flow Metab 1987;7:687-70l.
Cancer Neurology in Clinical Practice by Charles J. Vecht MD, PhD (auth.), David Schiff MD, Patrick Y. Wen MD (eds.)