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Download PDF by Jonathan L. Tilly, Jerome F. Strauss, Martin Tenniswood: Cell Death in Reproductive Physiology

By Jonathan L. Tilly, Jerome F. Strauss, Martin Tenniswood

ISBN-10: 1461219442

ISBN-13: 9781461219446

ISBN-10: 146127351X

ISBN-13: 9781461273516

The legislation of telephone loss of life in a number of reproductive tissues, as in different ma­ jor organ structures of the physique, has develop into a focus of analysis job in lots of laboratories over the last few years. As such, the necessity for a "for­ mal" assembly to spotlight contemporary paintings during this box, in addition to to combine wisdom from different resources (such as investigators engaged on telephone dying in melanoma and immune functionality) within the huge context of deciding on con­ served pathways that coordinate life-and-death judgements in varied telephone forms, turned obvious. hence, the objectives of the medical Committee of the overseas Symposium on telephone dying in Reproductive body structure, spon­ sored via Serono Symposia united states, have been already predetermined through this desire. easily said, we sought to assemble for the 1st time a opt for cohort of reproductive biologists and cellphone dying researchers, many yet now not all cho­ sen in accordance with their pioneering efforts in elucidating the elemental points of apoptosis in reproductive and nonreproductive tissues, as a method to re­ view the present prestige of the sector, foster new principles, and advertise medical collaborations. within the resulting chapters of this ebook, summaries of labor dis­ stubborn on the assembly are awarded to stress either the range and the similarities within the incidence and rules of apoptosis in tissues of the female and male reproductive systems.

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Additional info for Cell Death in Reproductive Physiology

Example text

Growing evidence suggests that survival of cells in the C. elegans reproductive system (as well as in vertebrate reproductive systems) is regulated by many of the same genes shown to control survival of somatic cells. In C. elegans, the cell death program in the germline is dependent upon oocyte production, and accounts for over onehalf of all germ cell outcomes. Significantly, the genetic program regulating cell death is not only conserved between soma and germline, it is conserved between mammals and nematodes.

14) reported that ablation of bC/-2 gene expression 3. 8. 5-dpc PGCs in culture. Cells were not immunostained at the beginning of culture (A) but became strongly positive after 16-18 h of culure (B). ) against mouse BCL-2 p25 protein was employed. Magnification, 500X. decreases the number of oocytes and primordial follicles endowed in mouse ovaries. Using RT-PCR (data not shown), immunohistochemistry, and Western blotting (Figs. 9), we did not obtain evidence that addition of MR(K) TO c lL. 9.

The vertebrate ovary. New York; Plenum Press, 1978;83-120. 2. Peters H, McNatty K. Atresia. In: Peters H, McNatty K, eds. The ovary. London: Granada Publishing, 1980;98-106. 3. Borum, K. Oogenesis in the mouse. A study of the meiotic prophase. Exp Cell Res 1961;24:495-507. 4. Bakken AH, McClanahan M. Patterns of RNA synthesis in early meiotic prophase oocytes from fetal mouse ovaries. Chromosoma 1978;67:21-40. 5. Tam P, Snow MHL. Proliferation and migration of primordial germ cells duriong compensatory growth in mouse embryos.

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Cell Death in Reproductive Physiology by Jonathan L. Tilly, Jerome F. Strauss, Martin Tenniswood


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